13523-86-9
13523-86-9
Chemical Structure
Pindolol
Synonym(s): LB-46
- CAS No.: 13523-86-9
- Formula:C14H20N2O2
- Molecular Weight:248.32
IUPAC Name: 1-((1H-indol-4-yl)oxy)-3-(isopropylamino)propan-2-ol
InChIKey: JZQKKSLKJUAGIC-UHFFFAOYSA-N
SMILES: OC(CNC(C)C)COC1=CC=CC2=C1C=CN2
Biological Activity: Pindolol (LB-46) is the antagonist for 5-HT 1A (Ki=33 nM) and 5-HT 1B. Pindolol is the antagonist for β1/β2-adrenergic receptor. Pindolol exhibits anti-anxiety and antidepressant effects[1][2].
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Pindolol | 99.92% | Pindolol (LB-46) is the antagonist for 5-HT 1A (Ki=33 nM) and 5-HT 1B. Pindolol is the antagonist for β1/β2-adrenergic receptor. Pindolol exhibits anti-anxiety and antidepressant effects. | ||||||||||||||||||||
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Pindolol (Standard) | 99.04% | Pindolol (Standard) is the analytical standard of Pindolol. This product is intended for research and analytical applications. Pindolol (LB-46) is the antagonist for 5-HT 1A (Ki=33 nM) and 5-HT 1B. Pindolol is the antagonist for β1/β2-adrenergic receptor. Pindolol exhibits anti-anxiety and antidepressant effects. | ||||||||||||||||||||
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Pindolol-d7 | Pindolol-d7 (LB-46-d7) is the deuterium labeled Pindolol. Pindolol (LB-46) is the antagonist for 5-HT 1A (Ki=33 nM) and 5-HT 1B. Pindolol is the antagonist for β1/β2-adrenergic receptor. Pindolol exhibits anti-anxiety and antidepressant effects. | |||||||||||||||||||||
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References
- [1]. Patkar OL, et al., Pindolol Rescues Anxiety-Like Behavior and Neurogenic Maladaptations of Long-Term Binge Alcohol Intake in Mice. Front Behav Neurosci. 2019 Nov 29;13:264. [Content Brief]
- [2]. Fernandes E, et al., Pindolol is a potent scavenger of reactive nitrogen species. Life Sci. 2005 Sep 2;77(16):1983-92. [Content Brief]
