1357164-52-3
1357164-52-3
Chemical Structure
KUS121
- CAS No.: 1357164-52-3
- Formula:C22H16FN4NaO3S
- Molecular Weight:458.44
IUPAC Name: sodium (E)-4-amino-3-((6-(4-fluoro-2-methylphenyl)pyridin-3-yl)diazenyl)naphthalene-1-sulfonate
InChIKey: OEEZHMGRDYLKGJ-JGUILPGDSA-M
SMILES: O=S(C1=C2C=CC=CC2=C(N)C(/N=N/C3=CC=C(C4=CC=C(C=C4C)F)N=C3)=C1)(O[Na])=O
Biological Activity: KUS121, a valosin-containing protein (VCP, p97) modulator with significant neuroprotective effects, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KUS121 | 99.76% | KUS121, a valosin-containing protein (VCP, p97) modulator with significant neuroprotective effects, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress. | ||||||||||||||||||||
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References
- [1]. KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress. Sci Rep. 2017 Mar 20:7:44873. [Content Brief]
- [2]. Hisanori Kinoshita, et al. KUS121, a valosin-containing protein modulator, attenuates ischemic stroke via preventing ATP depletion. Sci Rep. 2019 Aug 8;9(1):11519. [Content Brief]
Keywords
