13649-57-5
Chemical Structure
21-Desacetyldeflazacort
Synonym(s): 21-desDFZ
- CAS No.: 13649-57-5
- Formula:C23H29NO5
- Molecular Weight:399.48
IUPAC Name: (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d]oxazol-4-one
InChIKey: KENSGCYKTRNIST-RVUAFKSESA-N
SMILES: OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])OC(C)=N2)C)=O
Biological Activity: 21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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21-Desacetyldeflazacort | 98.43% | 21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration. | ||||||||||||||||||||
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21-Desacetyldeflazacort (Standard) | ≥98% | 21-Desacetyldeflazacort (Standard) is the analytical standard of 21-Desacetyldeflazacort. This product is intended for research and analytical applications. 21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration. | ||||||||||||||||||||
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21-Desacetyldeflazacort-d4 | 21-Desacetyldeflazacort-d4 (21-desDFZ-d4) is the deuterium labeled 21-Desacetyldeflazacort (HY-100085). 21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration. | |||||||||||||||||||||
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21-Desacetyldeflazacort-d5 | 99.34% | 21-Desacetyldeflazacort-d5 is the deuterium labeled 21-Desacetyldeflazacort. | ||||||||||||||||||||
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Similarity Score 0.88
HY-134520R21-Deacetoxy deflazacort (Standard) -
Similarity Score 0.86
HY-13609RDeflazacort (Standard) -
Similarity Score 0.82
HY-W654397Deflazacort-d3 -
Similarity Score 0.69
![(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity） (Standard) Chemical Structure](//file.medchemexpress.com/product_pic/hy-z2775r.gif)
HY-Z2775R(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity） (Standard) -
Similarity Score 0.68
HY-B0248Desonide -
Similarity Score 0.67
HY-19591Fluazacort -
Similarity Score 0.67
HY-11758016α-Hydroxyprednisolone -
Similarity Score 0.66
HY-125922(22R)-Budesonide -
Similarity Score 0.66
HY-13580RBudesonide (Standard) -
Explore the MedChemAI to find more analogs
![(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity） (Standard) Chemical Structure](http://file.medchemexpress.com/product_pic/hy-z2775r.gif)
