1379783-91-1
Chemical Structure
BMX-001
- CAS No.: 1379783-91-1
- Formula:C64H76Cl5MnN8O4
- Molecular Weight:1253.54
InChIKey: FVIXMTYHFFAYDY-UHFFFAOYSA-I
SMILES: CCCCOCC[N+]1=C(C=CC=C1)C2=C3C=CC4=C(C5=[N+](CCOCCCC)C=CC=C5)C6=[N]7[Mn+3]8([N-]34)[N-]9C(C(C%10=[N+](C=CC=C%10)CCOCCCC)=C%11C=CC2=[N]8%11)=CC=C9C(C%12=[N+](CCOCCCC)C=CC=C%12)=C7C=C6.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-]
Biological Activity: BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model. BMX-001 reduces apoptosis in human and murine islets. BMX-001 significantly improves static-glucose stimulated insulin secretion (sGSIS) responses in murine islets. BMX-001 can significantly restore euglycemia in murine islet studies in the presence of the MnSOD. BMX-001 reduces the generation of ROS in a murine islet isolation and culture model[1].
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BMX-001 | BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model. BMX-001 reduces apoptosis in human and murine islets. BMX-001 significantly improves static-glucose stimulated insulin secretion (sGSIS) responses in murine islets. BMX-001 can significantly restore euglycemia in murine islet studies in the presence of the MnSOD. BMX-001 reduces the generation of ROS in a murine islet isolation and culture model. | |||||||||||||||||||||
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Keywords
