138530-95-7
138530-95-7
Chemical Structure
(S)-Lansoprazole
Synonym(s): Levolansoprazole
- CAS No.: 138530-95-7
- Formula:C16H14F3N3O2S
- Molecular Weight:369.36
IUPAC Name: (S)-2-(((3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
InChIKey: MJIHNNLFOKEZEW-VWLOTQADSA-N
SMILES: O=[S@@](CC1=NC=CC(OCC(F)(F)F)=C1C)C2=NC3=CC=CC=C3N2
Biological Activity: (S)-Lansoprazole (Levolansoprazole) is an isoform of Lansoprazole (HY-13662), which is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[1][2].
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(S)-Lansoprazole | 98.90% | (S)-Lansoprazole (Levolansoprazole) is an isoform of Lansoprazole (HY-13662), which is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). | ||||||||||||||||||||
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References
- [1]. Kokufu, T., et al., Effects of lansoprazole on pharmacokinetics and metabolism of theophylline. Eur J Clin Pharmacol, 1995. 48(5): p. 391-5. [Content Brief]
- [2]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330. [Content Brief]
