1426953-23-2
Chemical Structure
Thailanstatin B
- No. CAS: 1426953-23-2
- Formula:C28H42ClNO9
- Molecular Weight:572.09
IUPAC Name: 2-((2S,4S,5R,6R)-6-((1E,3E)-5-((2S,3S,5R,6R)-5-((S,Z)-4-acetoxypent-2-enamido)-3,6-dimethyltetrahydro-2H-pyran-2-yl)-3-methylpenta-1,3-dien-1-yl)-4-(chloromethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)acetic acid
InChIKey: GAXKYFBEYVVCBB-FUDLAKRJSA-N
SMILES: C[C@@H](C[C@H]([C@H](O1)C)NC(/C=C\[C@H](C)OC(C)=O)=O)[C@@H]1C/C=C(C)/C=C/[C@@H]2[C@H]([C@@](O)(C[C@H](O2)CC(O)=O)CCl)O
Biological Activity: Thailanstatin B is a potent pre-mRNA splicing inhibitor (IC50=6.18 μM). Thailanstatin B shows antiproliferative activity[1].
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Thailanstatin B | Thailanstatin B is a potent pre-mRNA splicing inhibitor (IC50=6.18 μM). Thailanstatin B shows antiproliferative activity. | |||||||||||||||||||||
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Keywords
