143231-38-3
Chemical Structure
Glucobrassicin potassium
- CAS No.: 143231-38-3
- Formula:C16H19KN2O9S2
- Molecular Weight:486.56
IUPAC Name: potassium ((Z)-2-(1H-indol-3-yl)-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)thio)ethylidene)amino sulfate
InChIKey: NSURXWDIGUNLJB-AGVSWHMJSA-M
SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](S/C(CC2=CNC3=C2C=CC=C3)=N\OS(=O)(O[K])=O)O1
Biological Activity: Glucobrassicin potassium is an indole-based anticancer agent and plant growth-regulating hormone. Glucobrassicin potassium exerts its biological activity by disrupting the integrity of microtubule networks in both plant and mammalian cells. At high concentrations, Glucobrassicin potassium inhibits seed germination and root growth; it can also specifically induce apoptosis in mammalian cancer cells and interfere with the intercellular transmission of viruses that rely on microtubules. In plants, Glucobrassicin potassium can be catalyzed by myrosinase to release growth-regulating substances, exhibiting a concentration-dependent growth-regulating effect[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Glucobrassicin potassium | 95.39% | Glucobrassicin potassium is an indole-based anticancer agent and plant growth-regulating hormone. Glucobrassicin potassium exerts its biological activity by disrupting the integrity of microtubule networks in both plant and mammalian cells. At high concentrations, Glucobrassicin potassium inhibits seed germination and root growth; it can also specifically induce apoptosis in mammalian cancer cells and interfere with the intercellular transmission of viruses that rely on microtubules. In plants, Glucobrassicin potassium can be catalyzed by myrosinase to release growth-regulating substances, exhibiting a concentration-dependent growth-regulating effect. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.90
HY-N7659Glucobrassicin -
Similarity Score 0.80
HY-N17703Indolylmethyl-desulfoglucosinolate -
Similarity Score 0.75
HY-133902Neoglucobrassicin -
Similarity Score 0.75
HY-N86724-Methoxyglucobrassicin -
Similarity Score 0.74
HY-N4321RGlucotropaeolin potassium (Standard) -
Similarity Score 0.70
HY-N7257AGlucosinalbate potassium -
Similarity Score 0.68
HY-N8468Gluconasturtiin potassium -
Similarity Score 0.63
HY-N8933Glucolimnanthin -
Similarity Score 0.63
HY-N7257Glucosinalbate -
Explore the MedChemAI to find more analogs
References
- [1]. Guan P, et al. Anti-microtubule activity of the traditional Chinese medicine herb Northern Ban Lan (Isatis tinctoria) leads to glucobrassicin. J Integr Plant Biol. 2021 Dec;63(12):2058-2074. [Content Brief]
- [2]. Kutáček M. Glucobrassicin a potential inhibitor of unusual type affecting the germination and growth of plants; mechanism of its action[J]. Biologia plantarum, 1964, 6(2): 88-98.
