1433200-49-7
1433200-49-7
Chemical Structure
UNC2400
- CAS No.: 1433200-49-7
- Formula:C35H47N7O2
- Molecular Weight:597.79
IUPAC Name: N-((1,6-dimethyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-methyl-1H-indazole-4-carboxamide
InChIKey: IFSQHIRDVVFJSQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC=C(N3CCN(C(C)C)CC3)N=C2)=CC4=C1C=NN4C(C)C)N(CC5=C(CCC)C=C(C)N(C)C5=O)C
Biological Activity: UNC2400 is a close analog of UNC1999 with >1,000-fold lower potency than UNC1999 as a negative control for cell-based studies[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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UNC2400 | 99.92% | UNC2400 is a close analog of UNC1999 with >1,000-fold lower potency than UNC1999 as a negative control for cell-based studies. | ||||||||||||||||||||
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References
- [1]. Kyle D Konze, et al. An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1. ACS Chem Biol. 2013;8(6):1324-34. [Content Brief]
- [2]. Bowen Xu, et al. Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia. Blood. 2015 Jan 8;125(2):346-57. [Content Brief]
Keywords
