1443752-76-8
1443752-76-8
Chemical Structure
OP-1074
- CAS No.: 1443752-76-8
- Formula:C29H31NO4
- Molecular Weight:457.56
IUPAC Name: (S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-((R)-3-methylpyrrolidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol
InChIKey: KDVXAPCZVZMPMU-XBBWARJSSA-N
SMILES: OC1=CC2=C(C=C1)C(C)=C(C3=CC=C(O)C=C3)[C@H](C4=CC=C(OCCN5CC[C@@H](C)C5)C=C4)O2
Biological Activity: OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC50 values of 1.6 and 3.2 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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OP-1074 | 99.77% | OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC50 values of 1.6 and 3.2 nM, respectively. | ||||||||||||||||||||
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