1450595-86-4
1450595-86-4
Chemical Structure
DS-1971a
- CAS No.: 1450595-86-4
- Formula:C20H21ClFN5O3S
- Molecular Weight:465.93
IUPAC Name: 5-chloro-2-fluoro-4-(((1S,2R)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexyl)oxy)-N-(pyrimidin-4-yl)benzenesulfonamide
InChIKey: OJKONCJPCULNOW-DYVFJYSZSA-N
SMILES: O=S(C1=CC(Cl)=C(O[C@@H]2[C@@H](C3=CC=NN3C)CCCC2)C=C1F)(NC4=NC=NC=C4)=O
Biological Activity: DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor, with IC50s of 22.8 and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DS-1971a | 99.30% | DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor, with IC50s of 22.8 and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.53
HY-185334GNE-3565 -
Similarity Score 0.51
HY-126291GNE-616 -
Similarity Score 0.49
HY-12883PF 05089771 -
Similarity Score 0.47
HY-12883APF-05198007 -
Similarity Score 0.47
HY-157784XPC-7724 -
Similarity Score 0.46
HY-156596Aneratrigine -
Similarity Score 0.46
HY-178494Nav1.7-IN-19 -
Similarity Score 0.46
HY-185412SGK1-IN-9 -
Similarity Score 0.46
HY-156596AAneratrigine hydrochloride -
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