1450595-86-4

DS-1971a Chemical Structure
1450595-86-4

Chemical Structure

DS-1971a

  • CAS No.: 1450595-86-4
  • Formula:C20H21ClFN5O3S
  • Molecular Weight:465.93

IUPAC Name: 5-chloro-2-fluoro-4-(((1S,2R)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexyl)oxy)-N-(pyrimidin-4-yl)benzenesulfonamide

InChIKey: OJKONCJPCULNOW-DYVFJYSZSA-N

SMILES: O=S(C1=CC(Cl)=C(O[C@@H]2[C@@H](C3=CC=NN3C)CCCC2)C=C1F)(NC4=NC=NC=C4)=O

Biological Activity: DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor, with IC50s of 22.8 and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects[1].

Cat. No. Product Name Purity Description Pricing
HY-131182
DS-1971a 99.30% DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor, with IC50s of 22.8 and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects.
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