1458656-71-7
Chemical Structure
BI-2081
- CAS No.: 1458656-71-7
- Formula:C32H35FO6
- Molecular Weight:534.62
IUPAC Name: 2-((S)-6-(((R)-7-fluoro-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
InChIKey: VXNAMCLMCBLNOL-NFQMXDRXSA-N
SMILES: FC1=C(C(CC2)=C(C3=C(C=C(C=C3C)OCCC(C)(O)C)C)C=C1)[C@@H]2OC4=CC=C([C@@H](CO5)CC(O)=O)C5=C4
Biological Activity: BI-2081, a chemical probe, is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2[1].
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BI-2081 | BI-2081, a chemical probe, is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2. | |||||||||||||||||||||
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