1481646-76-7
1481646-76-7
Chemical Structure
HC-067047 hydrochloride
- CAS No.: 1481646-76-7
- Formula:C26H29ClF3N3O2
- Molecular Weight:507.98
InChIKey: OYEPECVNCLAKTO-UHFFFAOYSA-N
SMILES: CC1=C(C(NC2=CC(C(F)(F)F)=CC=C2)=O)C=C(C3=CC=CC=C3)N1CCCN4CCOCC4.Cl
Biological Activity: HC-067047 hydrochloride is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 48 nM, 133 nM, and 17 nM, respectively[1].
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HC-067047 hydrochloride | HC-067047 hydrochloride is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 48 nM, 133 nM, and 17 nM, respectively. | |||||||||||||||||||||
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References
Keywords
