150145-89-4
150145-89-4
Chemical Structure
(S)-MCPG
Synonym(s): (+)-MCPG
- CAS No.: 150145-89-4
- Formula:C10H11NO4
- Molecular Weight:209.20
IUPAC Name: (S)-4-(1-amino-1-carboxyethyl)benzoic acid
InChIKey: DNCAZYRLRMTVSF-JTQLQIEISA-N
SMILES: OC(C1=CC=C([C@](C)(N)C(O)=O)C=C1)=O
Biological Activity: (S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371)[1]. (S)-MCPG can be used for the study of the function of mGluRs in spatial learning[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S)-MCPG | 99.02% | (S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used for the study of the function of mGluRs in spatial learning. | ||||||||||||||||||||
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(S)-MCPG (Standard) | ≥98% | (S)-MCPG (Standard) is the analytical standard of (S)-MCPG (HY-100406). This product is intended for research and analytical applications. (S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used for the study of the function of mGluRs in spatial learning. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-100371R(RS)-MCPG (Standard) -
Similarity Score 0.84
HY-100617A(RS)-4CPG -
Similarity Score 0.82
HY-W0027354-Carboxyphenylacetic acid -
Similarity Score 0.82
HY-W010098Terephthalic acid -
Similarity Score 0.82
HY-W010098S1Terephthalic acid-13C2 -
Similarity Score 0.80
HY-200493-(4-Carboxyphenyl)propanoic acid -
Similarity Score 0.79
HY-W001939R4-Acetylbenzoic acid (Standard) -
Similarity Score 0.79
HY-W186811Ketoprofen impurity 7 -
Similarity Score 0.79
HY-W6141224-((Carboxymethyl)amino)benzoic acid -
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References
- [1]. Bernadett Boda, et al. Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome. Eur J Neurosci. 2014 Apr;39(7):1130-7. [Content Brief]
- [2]. F Bordi, et al. Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning. Neuropharmacology. 1996;35(11):1557-65. [Content Brief]
