15266-38-3
15266-38-3
Chemical Structure
Evocarpine
- CAS No.: 15266-38-3
- Formula:C23H33NO
- Molecular Weight:339.51
IUPAC Name: (Z)-1-methyl-2-(tridec-8-en-1-yl)quinolin-4(1H)-one
InChIKey: HWFYWIVOYBPLQU-SREVYHEPSA-N
SMILES: O=C1C=C(CCCCCCC/C=C\CCCC)N(C)C2=C1C=CC=C2
Biological Activity: Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca2+ influx through voltage-dependent calcium channels. Antimycobacterial activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Evocarpine | 99.88% | Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca2+ influx through voltage-dependent calcium channels. Antimycobacterial activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-N104561-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone -
Similarity Score 0.94
![1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone Chemical Structure](//file.medchemexpress.com/product_pic/hy-n0968.gif)
HY-N09681-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone -
Similarity Score 0.90
HY-N109074(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- -
Similarity Score 0.88
![1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone Chemical Structure](//file.medchemexpress.com/product_pic/hy-n9520.gif)
HY-N95201-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone -
Similarity Score 0.86
HY-N16361-Methyl-2-nonyl-4(1H)-quinolone -
Similarity Score 0.86
HY-N16381-Methyl-2-undecyl-4(1H)-quinolone -
Similarity Score 0.84
![1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone Chemical Structure](//file.medchemexpress.com/product_pic/hy-n9530.gif)
HY-N95301-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone -
Similarity Score 0.83
HY-N2517Dihydroevocarpine -
Similarity Score 0.82
HY-N4164Schinifoline -
Explore the MedChemAI to find more analogs
![1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone Chemical Structure](http://file.medchemexpress.com/product_pic/hy-n0968.gif)
![1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone Chemical Structure](http://file.medchemexpress.com/product_pic/hy-n9520.gif)
![1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone Chemical Structure](http://file.medchemexpress.com/product_pic/hy-n9530.gif)
References
- [1]. J Yamahar, et al. The vasorelaxant effect of evocarpine in isolated aortic strips: mode of action. Eur J Pharmacol. 1988 Oct 11;155(1-2):139-43. [Content Brief]
- [2]. C Hochfellner, et al. Antagonistic effects of indoloquinazoline alkaloids on antimycobacterial activity of evocarpine. J Appl Microbiol. 2015 Apr;118(4):864-72. [Content Brief]
