1542213-00-2

NCT-502 Chemical Structure
1542213-00-2

Chemical Structure

NCT-502

  • CAS No.: 1542213-00-2
  • Formula:C18H20F3N5S
  • Molecular Weight:395.45

IUPAC Name: N-(4,6-dimethylpyridin-2-yl)-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carbothioamide

InChIKey: HHKPPMSUPATMKP-UHFFFAOYSA-N

SMILES: S=C(NC1=NC(C)=CC(C)=C1)N2CCN(CC2)C3=NC=C(C=C3)C(F)(F)F

Biological Activity: NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH[1].

Cat. No. Product Name Purity Description Pricing
HY-117240 		NCT-502 98.59% NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH.
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