1601496-05-2
1601496-05-2
Chemical Structure
GSK-843
Synonym(s): GSK'843
- CAS No.: 1601496-05-2
- Formula:C19H15N5S2
- Molecular Weight:377.49
IUPAC Name: 3-(benzo[d]thiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine
InChIKey: BPKSNNJTKPIZKR-UHFFFAOYSA-N
SMILES: NC1=NC=C(C2=CC(C)=NN2C)C3=C1C(C4=CC=C(SC=N5)C5=C4)=CS3
Biological Activity: GSK-843 (GSK'843) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM. GSK-843 can be used for the research of inflammation[1][2].
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GSK-843 | 99.53% | GSK-843 (GSK'843) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM. GSK-843 can be used for the research of inflammation. | ||||||||||||||||||||
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