160588-45-4
160588-45-4
Chemical Structure
DMP-543
Synonym(s): XR-543
- CAS No.: 160588-45-4
- Formula:C26H18F2N2O
- Molecular Weight:412.43
IUPAC Name: 10,10-bis((2-fluoropyridin-4-yl)methyl)anthracen-9(10H)-one
InChIKey: MUJBUUDUXGDXLW-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2)C(CC3=CC(F)=NC=C3)(CC4=CC(F)=NC=C4)C5=CC=CC=C15
Biological Activity: DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer[1][2].
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DMP-543 | 99.96% | DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer. | ||||||||||||||||||||
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DMP-543 (Standard) | ≥98% | DMP-543 (Standard) is the analytical standard of DMP-543 (HY-108590). This product is intended for research and analytical applications. DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer. | ||||||||||||||||||||
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References
- [1]. Ipavec V, et al. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus. Pharmacol Res. 2011 Oct;64(4):397-409. [Content Brief]
- [2]. Zaczek R, et al. Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)-9(10H)-anthracenone: comparison to linopirdine. J Pharmacol Exp Ther. 1998 May;285(2):724-30. [Content Brief]
