1622159-00-5
1622159-00-5
Chemical Structure
BI-11634
- CAS No.: 1622159-00-5
- Formula:C22H22ClN4NaO4
- Molecular Weight:464.88
IUPAC Name: (R)-N-(1-(5-chloro-3l2-benzo[d]imidazol-2-yl)-2-methoxyethyl)-3-methyl-4-(3-oxomorpholino)benzamide, sodium salt
InChIKey: OJSUHLVJVGHFKW-FERBBOLQSA-M
SMILES: O=C(C1=CC=C(C(C)=C1)N2C(COCC2)=O)N[C@@H](COC)C3=NC4=CC=C(C=C4[N-]3)Cl.[Na+]
Biological Activity: BI-11634 is an orally active factor Xa inhibitor and a CYP3A4 substrate. The apparent Km values for BI-11634 metabolism are 23 μM in human liver microsomes (HLMs) and 7.6 μM with recombinant CYP3A4. BI-11634 can be used for thromboembolic disease and CYP3A4-mediated drug metabolism research[1].
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BI-11634 | BI-11634 is an orally active factor Xa inhibitor and a CYP3A4 substrate. The apparent Km values for BI-11634 metabolism are 23 μM in human liver microsomes (HLMs) and 7.6 μM with recombinant CYP3A4. BI-11634 can be used for thromboembolic disease and CYP3A4-mediated drug metabolism research. | |||||||||||||||||||||
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