1628502-91-9
1628502-91-9
Chemical Structure
MW-150
Synonym(s): MW01-18-150SRM
- CAS No.: 1628502-91-9
- Formula:C24H23N5
- Molecular Weight:381.47
IUPAC Name: 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine
InChIKey: CIIVUDIZZJLXCN-UHFFFAOYSA-N
SMILES: CN1CCN(C2=NN=C(C3=CC=C4C=CC=CC4=C3)C(C5=CC=NC=C5)=C2)CC1
Biological Activity: MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MW-150 | 99.38% | MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.98
HY-120111AMW-150 hydrochloride -
Similarity Score 0.96
HY-120111BMW-150 dihydrochloride dihydrate -
Similarity Score 0.76
HY-120796MW108 hydrochloride -
Similarity Score 0.63
HY-141889MLKL-IN-2 -
Similarity Score 0.59
HY-111203TT-301 -
Similarity Score 0.59
HY-178323MW073 -
Similarity Score 0.56
HY-145045HPK1-IN-18 -
Similarity Score 0.54
HY-15628Hoechst 33258 analog 5 -
Similarity Score 0.53
HY-D3099CSMPP -
Explore the MedChemAI to find more analogs
