1628502-91-9
1628502-91-9
Chemical Structure
MW-150
Synonym(s): MW01-18-150SRM
- CAS No.: 1628502-91-9
- Formula:C24H23N5
- Molecular Weight:381.47
IUPAC Name: 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine
InChIKey: CIIVUDIZZJLXCN-UHFFFAOYSA-N
SMILES: CN1CCN(C2=NN=C(C3=CC=C4C=CC=CC4=C3)C(C5=CC=NC=C5)=C2)CC1
Biological Activity: MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MW-150 | 99.89% | MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia. | ||||||||||||||||||||
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References
Keywords
