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Cat. No.: HY-145045

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HPK1-IN-18

HPK1-IN-18 is an HPK1 kinase inhibitor with anticancer cell activity. HPK1-IN-18 inhibits HPK1 kinase activity. HPK1-IN-18 can be used for cancer research.

For research use only. We do not sell to patients.

CAS No.: 2403598-42-3
Formula: C₂₄H₂₄N₄
Molecular Weight:368.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

HPK1-IN-18 Chemical Structure

CAS No.: 2403598-42-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

HPK1-IN-18 is an HPK1 kinase inhibitor with anticancer cell activity. HPK1-IN-18 inhibits HPK1 kinase activity. HPK1-IN-18 can be used for cancer research^[1].

IC₅₀ & Target

^[1]

HPK1

19 nM (IC₅₀)

All MAP4K Isoforms :

In Vitro

HPK1-IN-18 (compound 1) exhibits an enzymatic binding IC₅₀ of 19 nM against HPK1^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2403598-42-3
Molecular Weight 368.47
Formula C₂₄H₂₄N₄
SMILES

CN(CC1)CCN1C2=CC=C(C=C2)C3=CN=C(NC=C4C5=CC=CC=C5)C4=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li J, et al. Pyrrolo [2,3-b] pyridines or pyrrolo [2,3-b] pyrazines as hpk1 inhibitor and the use thereof. International Patent WO2019238067A1. Published December 19, 2019.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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HPK1-IN-18

All MAP4K Isoforms

Biological Activity

Description

IC50 & Target

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HPK1-IN-18 Related Classifications

HY-145045 Related Classifications

Bioz

Keywords

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