1628784-54-2
1628784-54-2
Chemical Structure
BG47
- CAS No.: 1628784-54-2
- Formula:C25H22N4O2S
- Molecular Weight:442.53
InChIKey: PNYUFPRPRATUNE-BYYHNAKLSA-N
SMILES: O=C(C1=CC=C(C=C1)/N=N/C2=CC=C(N(C)C)C=C2)NC3=C(O)C=CC(C4=CC=CS4)=C3
Biological Activity: BG47 is a prototypical histone deacetylases HDAC1 and HDAC2 selective, optoepigenetic probe. BG47 can bind to and competitively inhibits the deacetylase activity of HDAC targets upon a light-induced trans-to-cis isomerization, and increases Histone Methyltransferase H3K9 acetylation. BG47 can be used for neurological disease research[1].
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BG47 | BG47 is a prototypical histone deacetylases HDAC1 and HDAC2 selective, optoepigenetic probe. BG47 can bind to and competitively inhibits the deacetylase activity of HDAC targets upon a light-induced trans-to-cis isomerization, and increases Histone Methyltransferase H3K9 acetylation. BG47 can be used for neurological disease research. | |||||||||||||||||||||
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References
Keywords
