1643368-58-4
1643368-58-4
Chemical Structure
BMS-986142
- CAS No.: 1643368-58-4
- Formula:C32H30F2N4O4
- Molecular Weight:572.60
IUPAC Name: (S)-6-fluoro-5-((R)-3-(8-fluoro-1-methyl-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-2-methylphenyl)-2-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide
InChIKey: ZRYMMWAJAFUANM-INIZCTEOSA-N
SMILES: O=C1C2=C(C(F)=CC=C2)N(C)C(N1C3=C([C@]([C@]4=C(F)C=C(C(N)=O)C5=C4C6=C(C[C@@H](C(C)(C)O)CC6)N5)=CC=C3)C)=O
Biological Activity: BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM.
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BMS-986142 | 99.38% | BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM. | ||||||||||||||||||||
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BMS-986142 (Standard) | ≥98% | BMS-986142 (Standard) is the analytical standard of BMS-986142 (HY-101856). This product is intended for research and analytical applications. BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM. | ||||||||||||||||||||
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Keywords
