2. Protein Tyrosine Kinase/RTK
  3. TAM Receptor
  4. TAM-IN-2

TAM-IN-2 is a TAM inhibitor extracted from patent US 20170275290 A1, pyrrolotriazine compound 0904.

For research use only. We do not sell to patients.

TAM-IN-2 Chemical Structure

TAM-IN-2 Chemical Structure

CAS No. : 2135642-56-5

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Based on 1 publication(s) in Google Scholar

TAM-IN-2 Related Antibodies

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Description

TAM-IN-2 is a TAM inhibitor extracted from patent US 20170275290 A1, pyrrolotriazine compound 0904[1].

Molecular Weight

583.59

Formula

C31H27F2N7O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CN(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(C4=C5C(N)=NC=NN5C(C6CCN(C(C)=O)CC6)=C4)C(F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (8.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7135 mL 8.5677 mL 17.1353 mL
5 mM 0.3427 mL 1.7135 mL 3.4271 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7135 mL 8.5677 mL 17.1353 mL 42.8383 mL
5 mM 0.3427 mL 1.7135 mL 3.4271 mL 8.5677 mL
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TAM-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAM-IN-22135642-56-5TAM ReceptorTyro3AxlMerInhibitorinhibitorinhibit

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