16941-32-5
Chemical Structure
Glucagon (1-29), bovine, human
Synonym(s): Glucagon
- CAS No.: 16941-32-5
- Formula:C153H225N43O49S
- Molecular Weight:3482.75
SMILES: O=C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC7=CNC=N7)N
Biological Activity: Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation[2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Glucagon (1-29), bovine, human | 99.91% | Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation. | ||||||||||||||||||||
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Similarity Score 0.99
HY-P0082AGlucagon (1-29), bovine, human hydrochloride -
Similarity Score 0.97
HY-P4590(Glu20)-Glucagon (1-29) (human, rat, porcine) -
Similarity Score 0.97
HY-P4592(Glu24)-Glucagon (1-29) (human, rat, porcine) -
Similarity Score 0.96
HY-P4389(Asp28)-Glucagon (1-29) (human, rat, porcine) -
Similarity Score 0.96
HY-P4504(Des-Thr7)-Glucagon -
Similarity Score 0.96
HY-P4502(Des-Thr5)-Glucagon -
Similarity Score 0.90
![[Des-His1,Glu9]-Glucagon amide Chemical Structure](//file.medchemexpress.com/product_pic/hy-p1143.gif)
HY-P1143[Des-His1,Glu9]-Glucagon amide -
Similarity Score 0.88
HY-P3469Dasiglucagon -
Similarity Score 0.86
HY-P2080GIP (1-30) amide,human -
Explore the MedChemAI to find more analogs
![[Des-His1,Glu9]-Glucagon amide Chemical Structure](http://file.medchemexpress.com/product_pic/hy-p1143.gif)
References
- [1]. Song WJ, et al. Glucagon regulates hepatic kisspeptin to impair insulin secretion. Cell Metab. 2014 Apr 1;19(4):667-81. [Content Brief]
- [2]. Hirota K, et al. Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor. J Biol Chem. 2003 Apr 11;278(15):13056-60. [Content Brief]
- [3]. Song KH, et al. Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in humanhepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis. Hepatology. 2006 Jan;43(1):117-25. [Content Brief]
