1732-37-2
Chemical Structure
Duclauxin
Synonym(s): NSC 258308
- CAS No.: 1732-37-2
- Formula:C29H22O11
- Molecular Weight:546.48
InChIKey: WBQDAYWQELBEPU-FTAQWXBTSA-N
SMILES: O=C1C2=C(O)C=C(C)C3=C2[C@]4([C@@]([C@]5(OC)[C@@]([C@H]4OC(C)=O)([H])C3=O)([H])C(C6=COC(C7=C(O)C=C(C)C5=C76)=O)=O)CO1
Biological Activity: Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. Duclauxin (10-30 μg/mL) inhibits mitochondrial respiration of P-388 tumor cells and nucleic acid synthesis in cell culture of Ehrlich cancer, the lymphadenomas NK/LI and L 5178, and sarcoma 37. Duclauxin also inhibits growth of wheat coleoptile.
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Duclauxin | Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. Duclauxin (10-30 μg/mL) inhibits mitochondrial respiration of P-388 tumor cells and nucleic acid synthesis in cell culture of Ehrlich cancer, the lymphadenomas NK/LI and L 5178, and sarcoma 37. Duclauxin also inhibits growth of wheat coleoptile. | |||||||||||||||||||||
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