177355-84-9
177355-84-9
Chemical Structure
DBeQ
Synonym(s): JRF 12
- CAS No.: 177355-84-9
- Formula:C22H20N4
- Molecular Weight:340.42
IUPAC Name: N2,N4-dibenzylquinazoline-2,4-diamine
InChIKey: QAIMUUJJAJBPCL-UHFFFAOYSA-N
SMILES: C1(NCC2=CC=CC=C2)=NC(NCC3=CC=CC=C3)=C4C=CC=CC4=N1
Biological Activity: DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor, with an IC50 value of 1.5 μM and 1.6 μM for p97(wt) and p97(C522A), respectively; DBeQ also inhibits Vps4 with an IC50 of 11.5 μM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DBeQ | 98.79% | DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor, with an IC50 value of 1.5 μM and 1.6 μM for p97(wt) and p97(C522A), respectively; DBeQ also inhibits Vps4 with an IC50 of 11.5 μM. | ||||||||||||||||||||
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