1801185-08-9
Chemical Structure
SR12418
- CAS No.: 1801185-08-9
- Formula:C31H30FNO3
- Molecular Weight:483.57
IUPAC Name: (S)-(3-((4-(tert-butoxy)phenoxy)methyl)-6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)(naphthalen-1-yl)methanone
InChIKey: JIWBEKKHQWSDNN-VWLOTQADSA-N
SMILES: O=C(N1CC2=C(C=C(F)C=C2)C[C@H]1COC3=CC=C(OC(C)(C)C)C=C3)C4=C5C=CC=CC5=CC=C4
Biological Activity: SR12418 is a REV-ERB-specific synthetic ligand with IC50s of 68 nM and 119 nM for REV-ERBα and REV-ERBβ, respectively. SR12418 can be used in experimental autoimmune encephalomyelitis (EAE) and colitis research[1][2].
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SR12418 | 99.94% | SR12418 is a REV-ERB-specific synthetic ligand with IC50s of 68 nM and 119 nM for REV-ERBα and REV-ERBβ, respectively. SR12418 can be used in experimental autoimmune encephalomyelitis (EAE) and colitis research. | ||||||||||||||||||||
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Keywords