1802977-61-2
Chemical Structure
GNE-140 racemate
- CAS No.: 1802977-61-2
- Formula:C25H23ClN2O3S2
- Molecular Weight:499.04
IUPAC Name: 3-((2-chlorophenyl)thio)-6-(4-morpholinophenyl)-6-(thiophen-3-yl)piperidine-2,4-dione
InChIKey: GLDDJXYFHWRGPI-UHFFFAOYSA-N
SMILES: O=C(C1SC2=CC=CC=C2Cl)NC(C3=CSC=C3)(C4=CC=C(N5CCOCC5)C=C4)CC1=O
Biological Activity: GNE-140 racemate (Compound 28) is an external racemization mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B), and it is also an interconformational isomer of GNE-140 (HY-118241). GNE-140 racemate is also an effective lactate dehydrogenase (LDH) inhibitor, with the IC50 values for LDHA and LDHB being 9 nM and 30 nM respectively. GNE-140 racemate can be used in cancer research[1].
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GNE-140 racemate | 99.25% | GNE-140 racemate (Compound 28) is an external racemization mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B), and it is also an interconformational isomer of GNE-140 (HY-118241). GNE-140 racemate is also an effective lactate dehydrogenase (LDH) inhibitor, with the IC50 values for LDHA and LDHB being 9 nM and 30 nM respectively. GNE-140 racemate can be used in cancer research. | ||||||||||||||||||||
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GNE-140 racemate (Standard) | ≥98% | GNE-140 racemate (Standard) is the analytical standard of GNE-140 racemate (HY-100742). This product is intended for research and analytical applications. GNE-140 racemate is an external racemic mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B). GNE-140 racemate is also an effective lactate dehydrogenase (LDH) inhibitor. | ||||||||||||||||||||
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