1811510-58-3
1811510-58-3
Chemical Structure
MAP4K4-IN-3
- CAS No.: 1811510-58-3
- Formula:C15H12ClN5
- Molecular Weight:297.74
IUPAC Name: 5-(6-amino-5-(4-chlorophenyl)pyridin-3-yl)pyrimidin-2-amine
InChIKey: KSQDIECZAQKQQW-UHFFFAOYSA-N
SMILES: NC1=NC=C(C2=CC(C3=CC=C(Cl)C=C3)=C(N)N=C2)C=N1
Biological Activity: MAP4K4-IN-3 (Compound 17) is a potent and selective MAP4K4 inhibitor with an IC50 of 14.9 nM in kinase assay, an IC50 of 470 nM in cell assay. Antidiabetic agent[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MAP4K4-IN-3 | 99.77% | MAP4K4-IN-3 (Compound 17) is a potent and selective MAP4K4 inhibitor with an IC50 of 14.9 nM in kinase assay, an IC50 of 470 nM in cell assay. Antidiabetic agent. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.86
HY-19562PF-06260933 -
Similarity Score 0.85
HY-19562APF-06260933 hydrochloride -
Similarity Score 0.65
HY-W2439824-(2-Aminopyrimidin-5-yl)benzoic acid -
Similarity Score 0.64
HY-123965PF-06745013 -
Similarity Score 0.62
HY-183078P6620 -
Similarity Score 0.62
HY-W1120921,4-Di(pyrimidin-5-yl)benzene -
Similarity Score 0.62
HY-132863FTO-IN-2 -
Similarity Score 0.62
HY-18062RPyrimethamine (Standard) -
Similarity Score 0.61
HY-123369BMI-1026 -
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