1817802-18-8
1817802-18-8
Chemical Structure
MPT0B390
- CAS No.: 1817802-18-8
- Formula:C17H17N3O5S
- Molecular Weight:375.40
IUPAC Name: (E)-N-hydroxy-3-(1-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)acrylamide
InChIKey: QPXOAQWHONRALN-FARCUNLSSA-N
SMILES: O=C(NO)/C=C/C1=CN=C(N(S(=O)(C2=CC=C(OC)C=C2)=O)CC3)C3=C1
Biological Activity: MPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability. MPT0B390, TIMP3 inducer, inhibits tumor growth, metastasis and angiogenesis. MPT0B390 shows antiproliferative activity against human colon cancer cell line HCT116 with the GI50 of 0.03 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MPT0B390 | 98.76% | MPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability. MPT0B390, TIMP3 inducer, inhibits tumor growth, metastasis and angiogenesis. MPT0B390 shows antiproliferative activity against human colon cancer cell line HCT116 with the GI50 of 0.03 μM. | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.61
HY-124295Imofinostat -
Similarity Score 0.54
HY-119118J-30 -
Similarity Score 0.52
HY-124595MPT0B098 -
Similarity Score 0.52
HY-128133MMP-8 inhibitor-1 -
Similarity Score 0.50
HY-101834RACT-462206 (Standard) -
Similarity Score 0.50
HY-14718AResminostat hydrochloride -
Similarity Score 0.49
HY-14718Resminostat -
Similarity Score 0.48
HY-174803WMJ-J-09 -
Similarity Score 0.47
HY-162955LSD1/HDAC-IN-1 -
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