182564-47-2
Chemical Structure
LY302148
- CAS No.: 182564-47-2
- Formula:C19H23FN4
- Molecular Weight:326.41
IUPAC Name: 5-fluoro-3-(1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)piperidin-4-yl)-1H-indole
InChIKey: RFIDURCIAHBFRJ-UHFFFAOYSA-N
SMILES: CN1N=CC(CCN2CCC(C3=CNC4=C3C=C(F)C=C4)CC2)=C1
Biological Activity: LY302148 is a receptor ligand for 5-HT1F. Compared to the Emax of 5-HT, LY302148 behaves as a partial agonist for the 5-HT1F receptor. In the [35S]GTPγS binding assay targeting human 5-HT1F receptors, LY302148 exhibits good potency with an EC50 value of 5.23 nM. LY302148 can be used in the research of migraine[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
LY302148 | LY302148 is a receptor ligand for 5-HT1F. Compared to the Emax of 5-HT, LY302148 behaves as a partial agonist for the 5-HT1F receptor. In the [35S]GTPγS binding assay targeting human 5-HT1F receptors, LY302148 exhibits good potency with an EC50 value of 5.23 nM. LY302148 can be used in the research of migraine. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
