1850276-58-2

IRAK4-IN-4 Chemical Structure
1850276-58-2

Chemical Structure

IRAK4-IN-4

  • CAS No.: 1850276-58-2
  • Formula:C22H16N2O2
  • Molecular Weight:340.37

IUPAC Name: 1-(7-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-phenylethane-1,2-dione

InChIKey: AHNNWZOVCRQAAH-UHFFFAOYSA-N

SMILES: O=C(C1=C(C2=CC=CC=C2)N=C3C=C(C)C=CN31)C(C4=CC=CC=C4)=O

Biological Activity: IRAK4-IN-4 (Compound 15) is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, with an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM. IRAK4-IN-4 can be used for research of autoimmune diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-114181 		IRAK4-IN-4 99.55% IRAK4-IN-4 (Compound 15) is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, with an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM. IRAK4-IN-4 can be used for research of autoimmune diseases.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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Keywords