185039-89-8
185039-89-8
Chemical Structure
PD0166285
- CAS No.: 185039-89-8
- Formula:C26H27Cl2N5O2
- Molecular Weight:512.43
IUPAC Name: 6-(2,6-dichlorophenyl)-2-((4-(2-(diethylamino)ethoxy)phenyl)amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
InChIKey: IFPPYSWJNWHOLQ-UHFFFAOYSA-N
SMILES: O=C1N(C)C2=NC(NC3=CC=C(OCCN(CC)CC)C=C3)=NC=C2C=C1C4=C(Cl)C=CC=C4Cl
Biological Activity: PD0166285, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC50 values of 24 and 72 nM, respectively. PD0166285 exhibits an IC50 of 3.433 μM for Chk1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PD0166285 | 99.46% | PD0166285, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC50 values of 24 and 72 nM, respectively. PD0166285 exhibits an IC50 of 3.433 μM for Chk1. | ||||||||||||||||||||
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References
Keywords
