18550-98-6
18550-98-6
Chemical Structure
3PO
- CAS No.: 18550-98-6
- Formula:C13H10N2O
- Molecular Weight:210.23
IUPAC Name: (E)-3-(pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one
InChIKey: UOWGYMNWMDNSTL-ONEGZZNKSA-N
SMILES: O=C(C1=CC=NC=C1)/C=C/C2=CC=CN=C2
Biological Activity: 3PO is an inhibitor of PFKFB3. 3PO attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. 3PO suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+ and NADH. 3PO can be used for the research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3PO | 99.85% | 3PO is an inhibitor of PFKFB3. 3PO attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. 3PO suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+ and NADH. 3PO can be used for the research of cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-110169(E/Z)-3PO -
Similarity Score 0.76
HY-111163NSC49652 -
Similarity Score 0.72
HY-W3971733-Hydroxy-1,3-di(pyridin-4-yl)prop-2-en-1-one -
Similarity Score 0.70
HY-121054Chalcone -
Similarity Score 0.70
HY-Y0598Rtrans-Chalcone (Standard) -
Similarity Score 0.69
HY-W2489901,2-Di(pyridin-4-yl)ethane-1,2-dione -
Similarity Score 0.69
HY-175263Aminochalcone 4AAF -
Similarity Score 0.69
HY-N7056R4'-Hydroxychalcone (Standard) -
Similarity Score 0.69
HY-101285RDMU2139 (Standard) -
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