18550-98-6
Chemical Structure
3PO
- CAS No.: 18550-98-6
- Formula:C13H10N2O
- Molecular Weight:210.23
IUPAC Name: (E)-3-(pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one
InChIKey: UOWGYMNWMDNSTL-ONEGZZNKSA-N
SMILES: O=C(C1=CC=NC=C1)/C=C/C2=CC=CN=C2
Biological Activity: 3PO is an inhibitor of PFKFB3. 3PO attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. 3PO suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+ and NADH. 3PO can be used for the research of cancer[1].
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3PO | 99.85% | 3PO is an inhibitor of PFKFB3. 3PO attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. 3PO suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+ and NADH. 3PO can be used for the research of cancer. | ||||||||||||||||||||
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Keywords