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  4. Chalcone

Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities.

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Chalcone Chemical Structure

Chalcone Chemical Structure

CAS No. : 94-41-7

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Based on 1 publication(s) in Google Scholar

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Chalcone Related Antibodies

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Description

Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities[1].

In Vitro

Chalcone derivatives are synthesized by Claisen-Shimidt base-catalyzed condensation of appropriate aromatic ketones or substituted aromatic ketones with benzaldehydes or substituted benzaldehydes[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chalcone Related Antibodies
Clinical Trial
Molecular Weight

208.26

Formula

C15H12O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(/C=C/C1=CC=CC=C1)C2=CC=CC=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (480.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8017 mL 24.0085 mL 48.0169 mL
5 mM 0.9603 mL 4.8017 mL 9.6034 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.8017 mL 24.0085 mL 48.0169 mL 120.0423 mL
5 mM 0.9603 mL 4.8017 mL 9.6034 mL 24.0085 mL
10 mM 0.4802 mL 2.4008 mL 4.8017 mL 12.0042 mL
15 mM 0.3201 mL 1.6006 mL 3.2011 mL 8.0028 mL
20 mM 0.2401 mL 1.2004 mL 2.4008 mL 6.0021 mL
25 mM 0.1921 mL 0.9603 mL 1.9207 mL 4.8017 mL
30 mM 0.1601 mL 0.8003 mL 1.6006 mL 4.0014 mL
40 mM 0.1200 mL 0.6002 mL 1.2004 mL 3.0011 mL
50 mM 0.0960 mL 0.4802 mL 0.9603 mL 2.4008 mL
60 mM 0.0800 mL 0.4001 mL 0.8003 mL 2.0007 mL
80 mM 0.0600 mL 0.3001 mL 0.6002 mL 1.5005 mL
100 mM 0.0480 mL 0.2401 mL 0.4802 mL 1.2004 mL
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Chalcone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chalcone94-41-7BacterialParasiteanti-inflammatoryantioxidativeantibacterialanticanceranti-parasiticInhibitorinhibitorinhibit

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