186901-17-7
Chemical Structure
2B-(SP)
- CAS No.: 186901-17-7
- Formula:C71H123N26O29P
- Molecular Weight:1835.87
IUPAC Name: (6S,9S,12S,15S,18S,21S,24S,27S)-1,6-diamino-27-(((2S,8S,11S,14S)-1-((S)-2-(((S)-5-amino-1-(((S)-1-carboxy-3-methylbutyl)amino)-1,5-dioxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-11-(3-guanidinopropyl)-15-hydroxy-8-methyl-1,4,7,10,13-pentaoxo-2-((phosphonooxy
InChIKey: LBVCQYQHTKHZRY-APZQELAWSA-N
SMILES: N=C(N)NCCC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(NCC(N[C@@H](COP(O)(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: 2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) is readily phosphorylated by both the α and β isoforms of GSK-3[1].
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2B-(SP) | 2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) is readily phosphorylated by both the α and β isoforms of GSK-3. | |||||||||||||||||||||
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