1883429-22-8
1883429-22-8
Chemical Structure
BI-9564
- CAS No.: 1883429-22-8
- Formula:C20H23N3O3
- Molecular Weight:353.41
IUPAC Name: 4-(4-((dimethylamino)methyl)-2,5-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one
InChIKey: BJFSUDWKXGMUKA-UHFFFAOYSA-N
SMILES: CN(C)CC1=CC(OC)=C(C(C2=C3C=NC=C2)=CN(C)C3=O)C=C1OC
Biological Activity: BI-9564, a chemical probe, is a potent, selective and cell-permeable BRD9/BRD7 bromodomains inhibitor, with IC50s of 75 nM and 3.4 μM and Kds of 14 nM and 239 nM, respectively. BI-9564 has an IC50 of > 100 μM for BET family[1].
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BI-9564 | 98.96% | BI-9564, a chemical probe, is a potent, selective and cell-permeable BRD9/BRD7 bromodomains inhibitor, with IC50s of 75 nM and 3.4 μM and Kds of 14 nM and 239 nM, respectively. BI-9564 has an IC50 of > 100 μM for BET family. | ||||||||||||||||||||
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BI-9564 (Standard) | ≥98% | BI-9564 (Standard) is the analytical standard of BI-9564 (HY-100352). This product is intended for research and analytical applications. BI-9564, a chemical probe, is a potent, selective and cell-permeable BRD9/BRD7 bromodomains inhibitor, with IC50s of 75 nM and 3.4 μM and Kds of 14 nM and 239 nM, respectively. BI-9564 has an IC50 of > 100 μM for BET family. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-100351BI-7273 -
Similarity Score 0.70
HY-107446BI-7273 acid -
Similarity Score 0.68
HY-123616BI 7271 -
Similarity Score 0.67
HY-111905ABRD7-IN-1 free base -
Similarity Score 0.65
HY-111905BRD7-IN-1 -
Similarity Score 0.60
HY-175915BRD9 ligand-13 -
Similarity Score 0.58
HY-148116DN02 -
Similarity Score 0.56
HY-49393BRD9 ligand-6 -
Similarity Score 0.52
HY-137573Trotabresib -
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