18934-81-1
18934-81-1
Chemical Structure
Boc-12-Ado-OH
- CAS No.: 18934-81-1
- Formula:C17H33NO4
- Molecular Weight:315.45
IUPAC Name: 12-((tert-butoxycarbonyl)amino)dodecanoic acid
InChIKey: NNPOZNVKUHYVEJ-UHFFFAOYSA-N
SMILES: CC(OC(NCCCCCCCCCCCC(O)=O)=O)(C)C
Biological Activity: Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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Boc-12-Ado-OH | Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||||||||||||||||||||
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