1931-17-5
1931-17-5
Chemical Structure
DHFR-IN-28
- CAS No.: 1931-17-5
- Formula:C11H16ClN5
- Molecular Weight:253.73
IUPAC Name: 6,6-dimethyl-1-phenyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride
InChIKey: QDPFZWLLUCPLDI-UHFFFAOYSA-N
SMILES: NC1=NC(N)=NC(C)(C)N1C2=CC=CC=C2.Cl
Biological Activity: DHFR-IN-28 is an inhibitor of Plasmodium falciparum dihydrofolate reductase (DHFR), with a Ki value of 20.0 nM against wild-type pfDHFR. DHFR-IN-28 inhibits the growth of both wild-type and A16V+S108T mutant Plasmodium falciparum. DHFR-IN-28 is applicable for research related to malaria[1].
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DHFR-IN-28 | DHFR-IN-28 is an inhibitor of Plasmodium falciparum dihydrofolate reductase (DHFR), with a Ki value of 20.0 nM against wild-type pfDHFR. DHFR-IN-28 inhibits the growth of both wild-type and A16V+S108T mutant Plasmodium falciparum. DHFR-IN-28 is applicable for research related to malaria. | |||||||||||||||||||||
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References
Keywords
