199331-40-3
Chemical Structure
Etiprednol dicloacetate
Synonym(s): BNP 166; Etiprednol dichloroacetate
- No. CAS: 199331-40-3
- Formula:C24H30Cl2O6
- Molecular Weight:485.40
IUPAC Name: ethyl (8S,9S,10R,11S,13S,14S,17R)-17-(2,2-dichloroacetoxy)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate
InChIKey: QAIOVDNCIZSSSF-RFAJLIJZSA-N
SMILES: ClC(Cl)C(O[C@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([H])[C@@H](O)C2)([H])CC1)C)C(OCC)=O)=O
Biological Activity: Etiprednol dicloacetate (BNP 166) is an anti-inflammatory agent. Etiprednol dicloacetate inhibits eosinophil accumulation. Etiprednol dicloacetate can be used in the research of inflammatory airway diseases, such as asthma[1][2].
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Etiprednol dicloacetate | Etiprednol dicloacetate (BNP 166) is an anti-inflammatory agent. Etiprednol dicloacetate inhibits eosinophil accumulation. Etiprednol dicloacetate can be used in the research of inflammatory airway diseases, such as asthma. | |||||||||||||||||||||
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- [1]. István Kurucz, et al. Potency and specificity of the pharmacological action of a new, antiasthmatic, topically administered soft steroid, etiprednol dicloacetate (BNP-166). J Pharmacol Exp Ther. 2003 Oct;307(1):83-92. [Content Brief]
- [2]. A Miklós, et al. 28-day oral toxicity study with soft corticosteroid BNP-166 in rats and dogs, followed by a 14-day recovery period. Pharmazie. 2002 Feb;57(2):142-6. [Content Brief]
Keywords
