2010159-57-4
Chemical Structure
(S,R,S)-AHPC-PEG4-NH2
Synonym(s): VH032-PEG4-NH2; VHL Ligand-Linker Conjugates 4 ; E3 ligase Ligand-Linker Conjugates 7 Free Base
- CAS No.: 2010159-57-4
- Formula:C32H49N5O8S
- Molecular Weight:663.83
IUPAC Name: (2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: VSMWDQCRYIOFMX-UWPQIUOOSA-N
SMILES: O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCOCCOCCN
Biological Activity: (S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
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(S,R,S)-AHPC-PEG4-NH2 | 95.62% | (S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG4-NH2 (Standard) | ≥98% | (S,R,S)-AHPC-PEG4-NH2 (Standard) is the analytical standard of (S,R,S)-AHPC-PEG4-NH2 (HY-103604A). This product is intended for research and analytical applications. (S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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Similarity Score 0.99
HY-103604(S,R,S)-AHPC-PEG4-NH2 hydrochloride -
Similarity Score 0.95
HY-103602A(S,R,S)-AHPC-PEG3-NH2 -
Similarity Score 0.95
HY-103602R(S,R,S)-AHPC-PEG3-NH2 hydrochloride (Standard) -
Similarity Score 0.95
HY-W998297(S,R,S)-AHPC-CO-C-PEG5-amine hydrochloride -
Similarity Score 0.95
HY-103602B(S,R,S)-AHPC-PEG3-NH2 dihydrochloride -
Similarity Score 0.93
HY-187072(S,R,R)-VH032-CO-PEG4-NH2 -
Similarity Score 0.92
HY-103601R(S,R,S)-AHPC-PEG4-N3 (Standard) -
Similarity Score 0.91
HY-163209VH 032 amide-PEG6-amine hydrochloride -
Similarity Score 0.91
HY-180906(S,R,S)-AHPC-C2-PEG3-NH2 -
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