206885-38-3
206885-38-3
Chemical Structure
Ronopterin
Synonym(s): VAS203
- CAS No.: 206885-38-3
- Formula:C9H16N6O2
- Molecular Weight:240.26
IUPAC Name: (1R,2S)-1-(2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl)propane-1,2-diol
InChIKey: NDSDGUULXHNXGA-BYAPIUGTSA-N
SMILES: C[C@H](O)[C@@H](C1NC2=C(N)N=C(N)N=C2NC1)O
Biological Activity: Ronopterin (VAS203) is a NO Synthase inhibitor. Ronopterin can be used in research on diseases of the urogenital system and the nervous system[1][2].
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Ronopterin | Ronopterin (VAS203) is a NO Synthase inhibitor. Ronopterin can be used in research on diseases of the urogenital system and the nervous system. | |||||||||||||||||||||
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References
- [1]. Ott C, et al. Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers. Br J Clin Pharmacol. 2019 May;85(5):900-907. [Content Brief]
- [2]. Tegtmeier F, et al. Efficacy of Ronopterin (VAS203) in Patients with Moderate and Severe Traumatic Brain Injury (NOSTRA phase III trial): study protocol of a confirmatory, placebo-controlled, randomised, double blind, multi-centre study. Trials. 2020 Jan 14;21(1):80. [Content Brief]
