Ronopterin
Ronopterin (VAS203) is a NO Synthase inhibitor. Ronopterin can be used in research on diseases of the urogenital system and the nervous system.
For research use only. We do not sell to patients.
- CAS No.: 206885-38-3
- Formula: C9H16N6O2
- Molecular Weight:240.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 206885-38-3
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Molecular Weight 240.26
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Formula C9H16N6O2
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SMILES
C[C@H](O)[C@@H](C1NC2=C(N)N=C(N)N=C2NC1)O
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Synonyms
VAS203
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ott C, et al. Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers. Br J Clin Pharmacol. 2019 May;85(5):900-907. [Content Brief]
[2]. Tegtmeier F, et al. Efficacy of Ronopterin (VAS203) in Patients with Moderate and Severe Traumatic Brain Injury (NOSTRA phase III trial): study protocol of a confirmatory, placebo-controlled, randomised, double blind, multi-centre study. Trials. 2020 Jan 14;21(1):80. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)