2085780-87-4
2085780-87-4
Chemical Structure
FRM-024
- CAS No.: 2085780-87-4
- Formula:C22H22ClN5O2
- Molecular Weight:423.90
IUPAC Name: (5S,6R)-5-(4-chlorophenyl)-6-cyclopropyl-3-(6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl)-5,6-dihydro-4H-1,2,4-oxadiazine
InChIKey: IOQORVDNYPOZPL-VQTJNVASSA-N
SMILES: ClC1=CC=C(C=C1)[C@H]2[C@@H](C3CC3)ON=C(C4=CC=C(N5C=C(N=C5)C)C(OC)=N4)N2
Biological Activity: FRM-024 is a central nervous system-penetrant, orally active γ-secretase modulator and Aβ42 lowering agent. FRM-024 is used for the research of familial Alzheimer's disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FRM-024 | 99.45% | FRM-024 is a central nervous system-penetrant, orally active γ-secretase modulator and Aβ42 lowering agent. FRM-024 is used for the research of familial Alzheimer's disease. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-115726A(-)-FRM-024 -
Similarity Score 0.51
HY-117482BPN-15606 -
Similarity Score 0.50
HY-136866Aβ42-IN-2 -
Similarity Score 0.46
HY-145372γ-Secretase modulator 10 -
Similarity Score 0.46
HY-120449AZ4800 -
Similarity Score 0.46
HY-50900gamma-Secretase Modulators -
Similarity Score 0.46
HY-10016RE 2012 (Standard) -
Similarity Score 0.44
HY-185177Antifungal agent 156 -
Similarity Score 0.43
HY-147605Factor B-IN-3 -
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