2097938-59-3
Chemical Structure
Lerociclib dihydrochloride
Synonym(s): G1T38 dihydrochloride
- CAS No.: 2097938-59-3
- Formula:C26H36Cl2N8O
- Molecular Weight:547.52
IUPAC Name: 2'-((5-(4-isopropylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one dihydrochloride
InChIKey: IUIVDLVJNPANBY-UHFFFAOYSA-N
SMILES: O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C(C)C)CC6)C=C5)N=C43)CCCCC2.Cl.Cl
Biological Activity: Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lerociclib dihydrochloride | 98.51% | Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. | ||||||||||||||||||||
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Keywords
