2126136-98-7
2126136-98-7
Chemical Structure
CCT365623 hydrochloride
- CAS No.: 2126136-98-7
- Formula:C18H18ClNO4S3
- Molecular Weight:443.99
IUPAC Name: (5-((5-(methylsulfonyl)-[1,1'-biphenyl]-3-yl)sulfonyl)thiophen-2-yl)methanamine hydrochloride
InChIKey: MKBRQENFVVWIGU-UHFFFAOYSA-N
SMILES: NCC1=CC=C(S(=O)(C2=CC(C3=CC=CC=C3)=CC(S(=O)(C)=O)=C2)=O)S1.Cl
Biological Activity: CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCT365623 hydrochloride | 98.07% | CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-124674CCT365623 -
Similarity Score 0.48
HY-125375L-662583 -
Similarity Score 0.48
HY-157578COX-2-IN-38 -
Similarity Score 0.47
HY-143259BE1218 -
Similarity Score 0.47
HY-157583COX-2-IN-39 -
Similarity Score 0.47
HY-138101Desmethyl etoricoxib -
Similarity Score 0.47
![[1,1':4',1''-Terphenyl]-3,5-dicarboxylicacid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w543287.gif)
HY-W543287[1,1':4',1''-Terphenyl]-3,5-dicarboxylicacid -
Similarity Score 0.46
HY-103387DuP-697 -
Similarity Score 0.46
HY-W0041214-Biphenylsulfonyl chloride -
Explore the MedChemAI to find more analogs
![[1,1':4',1''-Terphenyl]-3,5-dicarboxylicacid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w543287.gif)
