2133294-96-7
2133294-96-7
Chemical Structure
Foliglurax monohydrochloride
Synonym(s): PXT002331 monohydrochloride
- CAS No.: 2133294-96-7
- Formula:C23H24ClN3O3S
- Molecular Weight:457.97
IUPAC Name: (E)-6-(3-morpholinopropyl)-2-(thieno[3,2-c]pyridin-6-yl)-4H-chromen-4-one oxime hydrochloride
InChIKey: LOBGNYCFXPNFJB-LUINMZRLSA-N
SMILES: O/N=C1C=C(C2=CC3=C(C=CS3)C=N2)OC4=CC=C(CCCN5CCOCC5)C=C\14.Cl
Biological Activity: Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM[1]. Antiparkinsonian effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Foliglurax monohydrochloride | 98.57% | Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. Antiparkinsonian effect. | ||||||||||||||||||||
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Foliglurax monohydrochloride (Standard) | ≥98% | Foliglurax monohydrochloride (Standard) is the analytical standard of Foliglurax (monohydrochloride) (HY-108703A). This product is intended for research and analytical applications. Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. AntiparKinsonian effect. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-108703Foliglurax -
Similarity Score 0.46
HY-D3091NRLyso -
Similarity Score 0.46
HY-123799SB-699393 -
Similarity Score 0.45
HY-117684Cabamiquine -
Similarity Score 0.44
HY-178926RAGE406R -
Similarity Score 0.43
HY-147329RAGE 229 -
Similarity Score 0.43
HY-139872eIF4A3-IN-4 -
Similarity Score 0.43
HY-146035AChE-IN-14 -
Similarity Score 0.42
HY-119990Fotocaine -
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