2147724-76-1
2147724-76-1
Chemical Structure
P8RI
Synonym(s): D-P8RI
- CAS No.: 2147724-76-1
- Formula:C51H77N13O9
- Molecular Weight:1016.24
InChIKey: LXYOOXZYRDPHLW-PJJIIYKISA-N
SMILES: O=C(N1[C@H](CCC1)C(N[C@H](C)C(N[C@H](CC(C)C)C(N[C@@H](C(N[C@H](C(C)C)C(N[C@@H](C(O)=O)CCCNC(N)=N)=O)=O)CC2=CC=CC=C2)=O)=O)=O)[C@H](NC([C@H](N)CCCCN)=O)CC3=CNC4=CC=CC=C34
Biological Activity: P8RI (D-P8RI) is a biomimetic peptide of CD31 and a CD31 agonist. P8RI binds to the juxtamembrane amino acid sequence of the ectodomain of CD31, shows an immunosuppressive effect through restoration of the CD31 inhibitory pathway[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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P8RI | 99.49% | P8RI (D-P8RI) is a biomimetic peptide of CD31 and a CD31 agonist. P8RI binds to the juxtamembrane amino acid sequence of the ectodomain of CD31, shows an immunosuppressive effect through restoration of the CD31 inhibitory pathway. | ||||||||||||||||||||
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References
- [1]. Diaz-Rodriguez S, et al. Coronary stent CD31-mimetic coating favours endothelialization and reduces local inflammation and neointimal development in vivo. Eur Heart J. 2021;42(18):1760-1769. [Content Brief]
- [2]. Sannier A, et al. A CD31-Derived Peptide Prevents the Development of Antibody-Mediated Lesions in a Rat Model of Aortic Allograft. Transplant Proc. 2021;53(2):746-749. [Content Brief]
Keywords
