2175953-98-5
Chemical Structure
Tau-aggregation and neuroinflammation-IN-1
- CAS No.: 2175953-98-5
- Formula:C25H20N2O7
- Molecular Weight:460.44
IUPAC Name: (R)-4-(8-acetyl-5,7-dihydroxy-3,4a,6-trimethyl-4-oxo-4,4a-dihydro-1H-benzofuro[3,2-f]indazol-1-yl)benzoic acid
InChIKey: AKUILIKFHHXNNL-VWLOTQADSA-N
SMILES: O=C(O)C1=CC=C(N2N=C(C)C3=C2C=C(OC4=C(C(C)=O)C(O)=C(C)C(O)=C45)[C@]5(C)C3=O)C=C1
Biological Activity: Tau-aggregation and neuroinflammation-IN-1 is a potent tau-aggregation and neuroinflammation inhibitor. Tau-aggregation and neuroinflammation-IN-1 exhibits remarkable inhibitory activities against AcPHF6 and full-length tau aggregation. Tau-aggregation and neuroinflammation-IN-1 has a low cytotoxicity and reduced NO release in LPS-stimulated BV2 cells. Tau-aggregation and neuroinflammation-IN-1 can reverse okadaic acid-induced memory impairment in rats[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tau-aggregation and neuroinflammation-IN-1 | 99.97% | Tau-aggregation and neuroinflammation-IN-1 is a potent tau-aggregation and neuroinflammation inhibitor. Tau-aggregation and neuroinflammation-IN-1 exhibits remarkable inhibitory activities against AcPHF6 and full-length tau aggregation. Tau-aggregation and neuroinflammation-IN-1 has a low cytotoxicity and reduced NO release in LPS-stimulated BV2 cells. Tau-aggregation and neuroinflammation-IN-1 can reverse okadaic acid-induced memory impairment in rats. | ||||||||||||||||||||
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