217645-70-0
217645-70-0
Chemical Structure
BX471
Synonym(s): ZK-811752
- CAS No.: 217645-70-0
- Formula:C21H24ClFN4O3
- Molecular Weight:434.89
IUPAC Name: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea
InChIKey: XQYASZNUFDVMFH-CQSZACIVSA-N
SMILES: O=C(N)NC1=CC(Cl)=CC=C1OCC(N2[C@H](C)CN(CC3=CC=C(F)C=C3)CC2)=O
Biological Activity: BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BX471 | 99.98% | BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
